(2-pyridyldithio)-PEG4-alcohol

Modify Date: 2024-01-04 07:31:01

(2-pyridyldithio)-PEG4-alcohol Structure
(2-pyridyldithio)-PEG4-alcohol structure
Common Name (2-pyridyldithio)-PEG4-alcohol
CAS Number 851961-99-4 Molecular Weight 319.44
Density N/A Boiling Point N/A
Molecular Formula C13H21NO4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2-pyridyldithio)-PEG4-alcohol


(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (2-Pyridyldithio)-PEG4-alcohol

 (2-pyridyldithio)-PEG4-alcohol Biological Activity

Description (2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H21NO4S2
Molecular Weight 319.44
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