RSV L-protein-IN-5

Modify Date: 2024-01-02 13:08:31

RSV L-protein-IN-5 Structure
RSV L-protein-IN-5 structure
Common Name RSV L-protein-IN-5
CAS Number 851658-28-1 Molecular Weight 556.66
Density N/A Boiling Point N/A
Molecular Formula C31H36N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RSV L-protein-IN-5


RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection[1].

 Names

Name RSV L-protein-IN-5

 RSV L-protein-IN-5 Biological Activity

Description RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection[1].
Related Catalog
Target

EC50: 0.1 μM ()[1]

References

[1]. Liuzzi M, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005 Oct;79(20):13105-15.  

 Chemical & Physical Properties

Molecular Formula C31H36N6O4
Molecular Weight 556.66