851658-28-1

851658-28-1 structure

Name: RSV L-protein-IN-5
Chemical Name: RSV L-protein-IN-5
CAS Number: 851658-28-1
Molecular Formula: C₃₁H₃₆N₆O₄
Molecular Weight: 556.66
Catalog: Signaling Pathways Anti-infection RSV
Create Date: 2023-09-19 21:39:55
Modify Date: 2024-01-02 13:08:31
RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection[1].

Name	RSV L-protein-IN-5

Description	RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> RSV
Target	EC50: 0.1 μM ()[1]
References	[1]. Liuzzi M, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005 Oct;79(20):13105-15.

Molecular Formula	C₃₁H₃₆N₆O₄
Molecular Weight	556.66