H4 Receptor antagonist 1
Modify Date: 2025-08-24 16:59:48
H4 Receptor antagonist 1 structure
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Common Name | H4 Receptor antagonist 1 | ||
|---|---|---|---|---|
| CAS Number | 848217-00-5 | Molecular Weight | 316.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H17ClN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of H4 Receptor antagonist 1H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. |
| Name | H4 Receptor antagonist 1 |
|---|
| Description | H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM. |
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| Related Catalog | |
| Target |
H4 receptor:19 nM (IC50) |
| In Vitro | H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM[1]. |
| In Vivo | H4 Receptor antagonist 1 indicates that metabolic stability in rat microsomes is very low with only 1% parent compound remaining after 10 min incubation[1]. |
| References |
| Molecular Formula | C16H17ClN4O |
|---|---|
| Molecular Weight | 316.79 |
| InChIKey | GUJLUPNSRRNJKP-UHFFFAOYSA-N |
| SMILES | Cc1nc(N2CCN(C)CC2)c2oc3ccc(Cl)cc3c2n1 |
| Storage condition | 2-8℃ |