EX-527 (S-enantiomer)

Modify Date: 2024-01-13 07:35:41

EX-527 (S-enantiomer) structure	Common Name	EX-527 (S-enantiomer)
	CAS Number	848193-68-0	Molecular Weight	248.708
	Density	1.4±0.1 g/cm3	Boiling Point	531.7±38.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₃ClN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	275.4±26.8 °C

Use of EX-527 (S-enantiomer)

Selisistat S-enantiomer (EX-527 S-enantiomer) is the S-enantiomer of Selisistat, with an IC50 of 123 nM for SIRT1. Selisistat S-enantiomer is much more potent than Selisistat R-enantiomer.

Name	(1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Synonym	More Synonyms

Description	Selisistat S-enantiomer (EX-527 S-enantiomer) is the S-enantiomer of Selisistat, with an IC50 of 123 nM for SIRT1. Selisistat S-enantiomer is much more potent than Selisistat R-enantiomer.
Related Catalog	Research Areas >> Cancer
Target	SIRT1:123 nM (IC50)
References	[1]. Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.

Density	1.4±0.1 g/cm3
Boiling Point	531.7±38.0 °C at 760 mmHg
Molecular Formula	C₁₃H₁₃ClN₂O
Molecular Weight	248.708
Flash Point	275.4±26.8 °C
Exact Mass	248.071640
PSA	59.87000
LogP	2.22
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.688

(S)-selisistat

OCZ

S1541_Selleck

(1S)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

cc-651

1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-, (1S)-

EX527

EX-527 S-enantiomer

EX-527 (S-enantiomer)

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: EX 527
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $462/10mM*1mLinDMSO

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EX-527 (S-enantiomer)

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