AP102

Modify Date: 2024-01-12 16:55:53

AP102 structure	Common Name	AP102
	CAS Number	846569-60-6	Molecular Weight	1313.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₆₆I₂N₁₂O₁₀S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AP102

AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research[1].

Name	AP102

Description	AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	SSTR2:0.63 nM (IC50) SSTR5:0.65 nM (IC50)
References	[1]. Tarasco E, et al. Effect of AP102, a subtype 2 and 5 specific somatostatin analog, on glucose metabolism in rats. Endocrine. 2017 Oct;58(1):124-133.

Molecular Formula	C₅₀H₆₆I₂N₁₂O₁₀S₂
Molecular Weight	1313.07

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AP102

Use of AP102

Names

AP102 Biological Activity

Chemical & Physical Properties