6-Aminophenanthridine

Modify Date: 2024-01-14 21:24:20

6-Aminophenanthridine Structure
6-Aminophenanthridine structure
Common Name 6-Aminophenanthridine
CAS Number 832-68-8 Molecular Weight 194.232
Density 1.3±0.1 g/cm3 Boiling Point 406.4±20.0 °C at 760 mmHg
Molecular Formula C13H10N2 Melting Point N/A
MSDS Chinese USA Flash Point 228.6±9.0 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of 6-Aminophenanthridine


6-Aminophenanthridine inhibits the protein folding activity of the ribosome (PFAR). 6-Aminophenanthridine competitively occludes the protein substrates from binding to rRNA and thereby inhibits PFAR[1].

 Names

Name phenanthridin-6-amine
Synonym More Synonyms

 6-Aminophenanthridine Biological Activity

Description 6-Aminophenanthridine inhibits the protein folding activity of the ribosome (PFAR). 6-Aminophenanthridine competitively occludes the protein substrates from binding to rRNA and thereby inhibits PFAR[1].
Related Catalog
References

[1]. Pang Y, et al. The antiprion compound 6-aminophenanthridine inhibits the protein folding activity of the ribosome by direct competition. J Biol Chem. 2013;288(26):19081-19089.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 406.4±20.0 °C at 760 mmHg
Molecular Formula C13H10N2
Molecular Weight 194.232
Flash Point 228.6±9.0 °C
Exact Mass 194.084396
PSA 39.64000
LogP 2.96
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.780

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
RIDADR UN 2811 6.1 / PGIII

 Synthetic Route

 Synonyms

6-Aminophenanthridine
Phenanthridin-6-ylamin
6-Phenanthridinamine
6-Amino-phenanthridin
phenanthridine-6-amine
Phenanthridine,6-amino
phenanthridin-6-ylamine
6-Phenanthridinamine (9CI)
9-Amino-phenanthridin
2-Aminobenzo(c)quinoline