14,15-EET

Modify Date: 2025-08-25 23:21:36

14,15-EET structure	Common Name	14,15-EET
	CAS Number	81276-03-1	Molecular Weight	320.46600
	Density	0.983g/cm3	Boiling Point	464.5ºC at 760 mmHg
	Molecular Formula	C₂₀H₃₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	155.7ºC

Use of 14,15-EET

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2].

Name	(+/-)14,15-epoxyeicosa-5z,8z,11z-trienoic acid
Synonym	More Synonyms

Description	14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	14,15-Epoxyeicosatrienoic acid (0-10 μM) 促进原代星形胶质细胞培养物中的 Aβ 摄取[1]。
In Vivo	14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) 可抑制小鼠脑小动脉中的血小板聚集[2]。 14,15-Epoxyeicosatrienoic acid (200 ng/ml) 注入海马体可逆转 6 个月大的雄性 FAD 小鼠大脑中的 Aβ 沉积[1]。
References	[1]. Chen W, et al. 14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease. J Neurosci. 2020 Oct 14;40(42):8188-8203. [2]. Heizer ML, et al. 14,15-Epoxyeicosatrienoic acid inhibits platelet aggregation in mouse cerebral arterioles. Stroke. 1991 Nov;22(11):1389-93.

Density	0.983g/cm3
Boiling Point	464.5ºC at 760 mmHg
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.46600
Flash Point	155.7ºC
Exact Mass	320.23500
PSA	49.83000
LogP	5.42790
Index of Refraction	1.501
Storage condition	-20°C

Hazard Codes	F,Xi
Risk Phrases	11-36/37/38
Safety Phrases	16-26-36
RIDADR	UN 1170 3/PG 2

14,15-Epoxyeicosatrienoic acid

14,15-epoxy-5,8,11-eicosatrienoicacid

14,15-EET

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 14,15-EET
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.