14,15-EET
Modify Date: 2024-01-06 22:50:26
14,15-EET structure
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Common Name | 14,15-EET | ||
|---|---|---|---|---|
| CAS Number | 81276-03-1 | Molecular Weight | 320.46600 | |
| Density | 0.983g/cm3 | Boiling Point | 464.5ºC at 760 mmHg | |
| Molecular Formula | C20H32O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 155.7ºC | |
Use of 14,15-EET14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2]. |
| Name | (+/-)14,15-epoxyeicosa-5z,8z,11z-trienoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 14,15-Epoxyeicosatrienoic acid (14,15-EET) is a metabolite of Arachidonic acid (HY-109590). 14,15-Epoxyeicosatrienoic acid is a potent inhibitor of in vivo platelet aggregation. 14,15-Epoxyeicosatrienoic acid facilitates astrocytic Aβ clearance. 14,15-Epoxyeicosatrienoic acid can be used for Alzheimer's Disease research[1][2]. |
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| Related Catalog | |
| In Vitro | 14,15-Epoxyeicosatrienoic acid (0-10 μM) 促进原代星形胶质细胞培养物中的 Aβ 摄取[1]。 |
| In Vivo | 14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) 可抑制小鼠脑小动脉中的血小板聚集[2]。 14,15-Epoxyeicosatrienoic acid (200 ng/ml) 注入海马体可逆转 6 个月大的雄性 FAD 小鼠大脑中的 Aβ 沉积[1]。 |
| References |
| Density | 0.983g/cm3 |
|---|---|
| Boiling Point | 464.5ºC at 760 mmHg |
| Molecular Formula | C20H32O3 |
| Molecular Weight | 320.46600 |
| Flash Point | 155.7ºC |
| Exact Mass | 320.23500 |
| PSA | 49.83000 |
| LogP | 5.42790 |
| Index of Refraction | 1.501 |
| Storage condition | -20°C |
| Hazard Codes | F,Xi |
|---|---|
| Risk Phrases | 11-36/37/38 |
| Safety Phrases | 16-26-36 |
| RIDADR | UN 1170 3/PG 2 |
| 14,15-Epoxyeicosatrienoic acid |
| 14,15-epoxy-5,8,11-eicosatrienoicacid |
| 14,15-EET |