Quinizarin

Modify Date: 2025-08-24 18:47:20

Quinizarin structure	Common Name	Quinizarin
	CAS Number	81-64-1	Molecular Weight	240.211
	Density	1.5±0.1 g/cm3	Boiling Point	465.3±40.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₈O₄	Melting Point	198-199 °C(lit.)
	MSDS	Chinese USA	Flash Point	249.3±23.8 °C
	Symbol	GHS09	Signal Word	Warning

Use of Quinizarin

Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2].

Name	quinizarin
Synonym	More Synonyms

Description	Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Fungal
In Vitro	1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1].
References	[1]. Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55. [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin. [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373.

Density	1.5±0.1 g/cm3
Boiling Point	465.3±40.0 °C at 760 mmHg
Melting Point	198-199 °C(lit.)
Molecular Formula	C₁₄H₈O₄
Molecular Weight	240.211
Flash Point	249.3±23.8 °C
Exact Mass	240.042252
PSA	74.60000
LogP	4.47
Vapour density	8.3 (vs air)
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.733
Water Solubility	<1 g/L (20 ºC)

Quinizarin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB6600000

CHEMICAL NAME :: Anthraquinone, 1,4-dihydroxy-

CAS REGISTRY NUMBER :: 81-64-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C14-H8-O4

MOLECULAR WEIGHT :: 240.22

WISWESSER LINE NOTATION :: L C666 BV IVJ DQ GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82067 No. of Facilities: 563 (estimated) No. of Industries: 10 No. of Occupations: 9 No. of Employees: 6634 (estimated)

Symbol	GHS09
Signal Word	Warning
Hazard Statements	H410
Precautionary Statements	P273-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	UN 3077 9 / PGIII
WGK Germany	2
RTECS	CB6600000
Packaging Group	II; III
Hazard Class	4.1
HS Code	2914610000

Precursor 9
CAS#:85-44-9 Phthalic anhydride CAS#:123-31-9 Hydroquinone CAS#:88-95-9 Phthaloyl chloride CAS#:28736-42-7 1,4-difluoroant...
CAS#:6119-74-0 9, 10-Anthracen... CAS#:26851-55-8 boric anhydride CAS#:106-48-9 4-Chlorophenol CAS#:51287-54-8 3-phenylsulfany...
CAS#:106-51-4 1,4-Benzoquinone
DownStream 9
CAS#:106752-92-5 1,4,9,10-tetram... CAS#:476-60-8 1,4,9,10-Anthra... CAS#:17648-03-2 1,4-Anthracened... CAS#:81-64-1 Quinizarin
CAS#:20253-58-1 1,4-dihydroxy-2... CAS#:22297-70-7 2-Anthracenesul... CAS#:23743-40-0 1,4-dihydroxy-2... CAS#:25060-18-8 9,10-Anthracene...
CAS#:23861-69-0 9,10-Anthracene...

HS Code	2914610000
Summary	2914610000 anthracene-9,10-dione。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0%

In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones.

Antimicrob. Agents Chemother. 51 , 1541-4, (2007)

We report that certain anthraquinones (AQs) reduce Streptococcus mutans biofilm formation on hydroxyapatite at concentrations below the MIC. Although AQs are known to generate reactive oxygen species,...

Synthesis and activity of substituted anthraquinones against a human filarial parasite, Brugia malayi.

J. Med. Chem. 48 , 2822-30, (2005)

Lymphatic filariasis (elephantiasis) is a global public health problem caused by the parasitic nematodes Wuchereria bancrofti and Brugia malayi. We have previously reported anthraquinones from daylily...

Synthesis of glycoside derivatives of hydroxyanthraquinone with ability to dissolve and inhibit formation of crystals of calcium oxalate. Potential compounds in kidney stone therapy.

Eur. J. Med. Chem. 45 , 1001-7, (2010)

Synthesis of glycosyl derivatives of hydroxyanthraquinones (6-10) potentially useful for kidney stone therapy is presented. These compounds were analyzed as inhibitors of calcium oxalate crystals form...

MFCD00001209

EINECS 201-368-7

1,4-hydroxyanthraquinone

QUINIZARINE

DSD ACID

smokeoranger

1,4-Dihydroxy-9,10-anthraquinone

Quinizarin

Chinizarin

1,4-Dihydroxy-9,10-anthracene-dione

1,4-Dihydroxyanthraquinone

9,10-Anthracenedione, 1,4-dihydroxy-

Quinizalin

QUINAZARIN

1,4-Doa

1,4-dihydroxyanthracene-9,10-dione

quiniazarine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Quinizarin
Price: Check
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Quinizarin
Price: ￥138.0/100g ￥448.0/500g
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Quinizarin
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
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DC Chemicals Limited
China
Product Name: Quinizarin
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,4-DIHYDROXYANTHRAQUINONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Quinizarin

Use of Quinizarin

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Quinizarin Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

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