Desoxycorticosterone pivalate

Modify Date: 2024-01-02 10:07:39

Desoxycorticosterone pivalate structure	Common Name	Desoxycorticosterone pivalate
	CAS Number	808-48-0	Molecular Weight	414.57800
	Density	1.111 g/cm3	Boiling Point	529.012ºC at 760 mmHg
	Molecular Formula	C₂₆H₃₈O₄	Melting Point	198-204ºC
	MSDS	N/A	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of Desoxycorticosterone pivalate

Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism[1][2].

Name	11-deoxycorticosterone pivalate
Synonym	More Synonyms

Description	Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Others
In Vivo	A starting dosage of 1.5 mg/kg Desoxycorticosterone pivalate (DOCP) is effective in controlling clinical signs and serum electrolyte concentrations in the majority of dogs with PH. An additional dose reduction often is needed to maintain an injection interval of 28-30 days. Young and growing animals seem to need higher dosages[1].
References	[1]. Sieber-Ruckstuhl NS, et al. Evaluation of a low-dose desoxycorticosterone pivalate treatment protocol for long-term management of dogs with primary hypoadrenocorticism. J Vet Intern Med. 2019 May;33(3):1266-1271. [2]. Masticatory Muscle Myositis: Pathogenesis, Diagnosis, and Treatment.

Density	1.111 g/cm3
Boiling Point	529.012ºC at 760 mmHg
Melting Point	198-204ºC
Molecular Formula	C₂₆H₃₈O₄
Molecular Weight	414.57800
Exact Mass	414.27700
PSA	60.44000
LogP	5.29290
Index of Refraction	1.534
Storage condition	-20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5021400

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-

CAS REGISTRY NUMBER :: 808-48-0

BEILSTEIN REFERENCE NO. :: 3174879

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C26-H38-O4

MOLECULAR WEIGHT :: 414.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 119 mg/kg/24W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Endocrine - changes in thyroid weight Related to Chronic Data - changes in testicular weight

REFERENCE :: AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 54,1954,1993

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332
Precautionary Statements	P261-P280-P301 + P312 + P330
RIDADR	NONH for all modes of transport

17α-hydroxyprog...

CAS#:68-96-2

Pivaloyl chloride

CAS#:3282-30-2

Desoxycorticost...

CAS#:808-48-0

Literature: Helvetica Chimica Acta, , vol. 34, p. 354,358

Precursor 2
CAS#:68-96-2 17α-hydroxyprog... CAS#:3282-30-2 Pivaloyl chloride
DownStream 0

21-pivaloyloxy-pregn-4-ene-3,20-dione

Desoxycorticosterone pivalate

neodin-depositum

MFCD00199992

21-Pivaloyloxy-pregn-4-en-3,20-dion

Percorten pivalate

deoxycorticosterone pivalate

percortenm

Desoxycortisone pivalate

DOC PIVALATE

docp

cortexonem

deoxycortonepivalate

desoxycortone pivalate

EINECS 212-366-0

DC Chemicals Limited
China
Product Name: Desoxycorticosterone pivalate
Price:
Purity: 98.0%
Stocking Period: 3 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Desoxycorticosterone pivalate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: Desoxycorticosterone pivalate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Desoxycorticosterone pivalate

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