Tetramethylguanidine

Modify Date: 2018-12-16 20:36:18

Tetramethylguanidine Structure
Tetramethylguanidine structure
Share to Facebook Share to Twitter Share to Linkedin
Common Name Tetramethylguanidine
CAS Number 80-70-6 Molecular Weight 115.177
Density 0.9±0.1 g/cm3 Boiling Point 163.2±9.0 °C at 760 mmHg
Molecular Formula C5H13N3 Melting Point -30 °C
MSDS Chinese USA Flash Point 60.0±0.0 °C
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

 Names

Name Tetramethylguanidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 163.2±9.0 °C at 760 mmHg
Melting Point -30 °C
Molecular Formula C5H13N3
Molecular Weight 115.177
Flash Point 60.0±0.0 °C
Exact Mass 115.110947
PSA 30.33000
LogP 0.41
Vapour Pressure 2.1±0.3 mmHg at 25°C
Index of Refraction 1.456
Storage condition 2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Air-sensitive.
Water Solubility miscible

 MSDS

Name: 1 1 3 3-Tetramethylguanidine 99% (gc) Material Safety Data Sheet
Synonym: Non
CAS: 80-70-6
Section 1 - Chemical Product MSDS Name:1 1 3 3-Tetramethylguanidine 99% (gc) Material Safety Data Sheet
Synonym:Non

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
80-70-6 1,1,3,3-Tetramethylguanidine 99% 201-302-7
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat as a caustic agent.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - HANDLING and STORAGE
Handling:
Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 80-70-6: Personal Protective Equipment Eyes: Wear chemical goggles and a face shield if splashing is possible.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: Not available.
Odor: Mild ammoniacal odor
pH: Not available.
Vapor Pressure: .26 hPa @ 25 deg C
Viscosity: mPas 20 deg C
Boiling Point: 160 - 162 deg C @ 760.00mm Hg
Freezing/Melting Point: <-30 deg C
Autoignition Temperature: 350 deg C ( 662.00 deg F)
Flash Point: 60 deg C ( 140.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: miscible with water
Specific Gravity/Density: .9180g/cm3
Molecular Formula: C5H13N3
Molecular Weight: 115.18

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents - strong acids - acid chlorides - acid anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 80-70-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1,1,3,3-Tetramethylguanidine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.*
Hazard Class: 8 (3)
UN Number: 2920
Packing Group: II
IMO
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.
Hazard Class: 8 (3)
UN Number: 2920
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE LIQUID, FLAMMABLE, N.O.S.
Hazard Class: 8
UN Number: 2920
Packing group: II

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 25 Avoid contact with eyes.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 80-70-6: 2
Canada
CAS# 80-70-6 is listed on Canada's DSL List.
CAS# 80-70-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 80-70-6 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger
Hazard Statements H226-H302-H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R10;R20/22;R34
Safety Phrases S26-S27-S36/37/39-S45-S16
RIDADR UN 2920 8/PG 2
WGK Germany 1
Packaging Group II
Hazard Class 8
HS Code 2942000000

 Synthetic Route

~%

Tetramethylguanidine Structure

Tetramethylguanidine

CAS#:80-70-6

Literature: Journal of Organic Chemistry, , vol. 72, # 11 p. 4067 - 4072

~%

Tetramethylguanidine Structure

Tetramethylguanidine

CAS#:80-70-6

Literature: Journal of the American Chemical Society, , vol. 98, p. 1870 - 1875

~%

Tetramethylguanidine Structure

Tetramethylguanidine

CAS#:80-70-6

Literature: US6683198 B1, ; Page column 3-4 ;

~%

Tetramethylguanidine Structure

Tetramethylguanidine

CAS#:80-70-6

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 141, p. 141

~%

Tetramethylguanidine Structure

Tetramethylguanidine

CAS#:80-70-6

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 141, p. 141

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles4

More Articles
CO2 capture systems based on saccharides and organic superbases.

Faraday Discuss. 183 , 429-44, (2015)

In this report, novel systems, based on highly abundant saccharides, D-mannose, D-glucose, β-cyclodextrin, alginic acid and mannitol, in combination with an organic superbase, tetramethylguanidine (TM...

Synth. Commun. 23 , 2323, (1993)

Tetrahedron 49 , 10061, (1993)