Emicerfont
Modify Date: 2024-01-09 10:35:01
Emicerfont structure
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Common Name | Emicerfont | ||
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| CAS Number | 786701-13-1 | Molecular Weight | 404.46500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EmicerfontEmicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM. |
| Name | 1-[1-[1-(4-methoxy-2-methylphenyl)-6-methyl-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]imidazolidin-2-one |
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| Synonym | More Synonyms |
| Description | Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM. |
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| Related Catalog | |
| Target |
IC50: 66 nM (CRF1 receptor)[1] |
| In Vitro | Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM[1]. |
| In Vivo | At concentration of 10 mg/kg, Emicerfont reduces i.c.v. CRF-induced gerbil forepaw treading and marmoset defensive postures. Emicerfont also reduces rat pup ultrasonic vocalization at concentration of 30 mg/kg[1]. |
| References |
| Molecular Formula | C22H24N6O2 |
|---|---|
| Molecular Weight | 404.46500 |
| Exact Mass | 404.19600 |
| PSA | 79.01000 |
| LogP | 2.88650 |
| Storage condition | 2-8℃ |
| unii-oj8eg4264p |
| emicerfont |