Olanzapine D3

Modify Date: 2024-01-31 11:27:59

Olanzapine D3 structure	Common Name	Olanzapine D3
	CAS Number	786686-79-1	Molecular Weight	315.45100
	Density	1.337g/cm3	Boiling Point	476.035ºC at 760 mmHg
	Molecular Formula	C₁₇H₁₇D₃N₄S	Melting Point	188-190ºC
	MSDS	N/A	Flash Point	241.697ºC

Use of Olanzapine D3

Olanzapine D3 (LY170053 D3) is the deuterium labeled Olanzapine. Olanzapine is 5-HT2 and D1/D2 antagonist. Olanzapine is an antipsychotic agent with anticholinergic properties[1]. Olanzapine induces autophagy, mitochondrial damage and mitophagy in human SH-SY5Y neuronal cell line[2].

Name	2-methyl-4-[4-(trideuteriomethyl)piperazin-1-yl]-5H-thieno[3,2-c][1,5]benzodiazepine
Synonym	More Synonyms

Description	Olanzapine D3 (LY170053 D3) is the deuterium labeled Olanzapine. Olanzapine is 5-HT2 and D1/D2 antagonist. Olanzapine is an antipsychotic agent with anticholinergic properties[1]. Olanzapine induces autophagy, mitochondrial damage and mitophagy in human SH-SY5Y neuronal cell line[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Signaling Pathways >> Autophagy >> Mitophagy Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Moore NA, et al. The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther. 1992 Aug;262(2):545-51. [2]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. Autophagy. 2014;10(12):2362-78.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Signaling Pathways >> Autophagy >> Mitophagy

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

References

[1]. Moore NA, et al. The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther. 1992 Aug;262(2):545-51.

[2]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. Autophagy. 2014;10(12):2362-78.

Density	1.337g/cm3
Boiling Point	476.035ºC at 760 mmHg
Melting Point	188-190ºC
Molecular Formula	C₁₇H₁₇D₃N₄S
Molecular Weight	315.45100
Flash Point	241.697ºC
Exact Mass	315.16000
PSA	59.11000
LogP	2.88860
Index of Refraction	1.709

Olanzapine-methyl-d3

2-methyl-4-(4-methyl-D3-piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine

Oliza-d3

Oltal-d3

Integrol-d3

Zyprexa-d3

Olanzapine-d3

Oleanz-d3

Lanzac-d3

Olanzapine D3

Use of Olanzapine D3

Names

Olanzapine D3 Biological Activity

Chemical & Physical Properties

Synonyms