7-Ethylcamptothecin

Modify Date: 2025-08-24 00:01:46

7-Ethylcamptothecin Structure
7-Ethylcamptothecin structure
Common Name 7-Ethylcamptothecin
CAS Number 78287-27-1 Molecular Weight 376.405
Density 1.4±0.1 g/cm3 Boiling Point 752.9±60.0 °C at 760 mmHg
Molecular Formula C22H20N2O4 Melting Point 236-241ºC
MSDS USA Flash Point 409.1±32.9 °C

 Use of 7-Ethylcamptothecin


7-Ethylcamptothecin is one of camptothecin analogues. camptothecin (CPT), a cytotoxic alkaloid isolated from Camptotheca acuminate, is shown to have strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models[1].

 Names

Name 7-Ethylcamptothecin
Synonym More Synonyms

 7-Ethylcamptothecin Biological Activity

Description 7-Ethylcamptothecin is one of camptothecin analogues. camptothecin (CPT), a cytotoxic alkaloid isolated from Camptotheca acuminate, is shown to have strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models[1].
Related Catalog
References

[1]. Wang, X.,et al. New Route for Conversion of Camptothecin to 7-Ethylcamptothecin and 7-Propylcamptothecin. Synthetic Communications, 2007,37(3), 519–523.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 752.9±60.0 °C at 760 mmHg
Melting Point 236-241ºC
Molecular Formula C22H20N2O4
Molecular Weight 376.405
Flash Point 409.1±32.9 °C
Exact Mass 376.142303
PSA 81.42000
LogP 2.60
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.713
Storage condition -20°C Freezer

 Safety Information

Hazard Codes T+
HS Code 2942000000

 Synthetic Route

 Customs

HS Code 2942000000

 Synonyms

SN 22
(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (S)-
20(S)-7-ethylcamptothecin
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
7-ethyl-20(S)-camptothecin
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (4S)-
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