2,2'-Azobis(2-methylpropionitrile)

Modify Date: 2025-08-21 09:58:16

2,2'-Azobis(2-methylpropionitrile) structure	Common Name	2,2'-Azobis(2-methylpropionitrile)
	CAS Number	78-67-1	Molecular Weight	164.208
	Density	1.0±0.1 g/cm3	Boiling Point	236.2±25.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₂N₄	Melting Point	102-104 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	96.6±23.2 °C
	Symbol	GHS02, GHS07, GHS08	Signal Word	Danger

Name	2,2'-Azobis(2-methylpropionitrile)
Synonym	More Synonyms

Density	1.0±0.1 g/cm3
Boiling Point	236.2±25.0 °C at 760 mmHg
Melting Point	102-104 °C (dec.)(lit.)
Molecular Formula	C₈H₁₂N₄
Molecular Weight	164.208
Flash Point	96.6±23.2 °C
Exact Mass	164.106201
PSA	72.30000
LogP	1.26
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.491
Stability	Stability Flammable solid. Shock sensitive. Thermally unstable. May be explosive in combination with acetone or heptane. Incompatible with oxidizing agents.
Water Solubility	Insoluble

2,2'-Azobis(2-methylpropionitrile) MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UG0800000

CHEMICAL NAME :: Propionitrile, 2,2'-azobis(2-methyl-

CAS REGISTRY NUMBER :: 78-67-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C8-H12-N4

MOLECULAR WEIGHT :: 164.24

WISWESSER LINE NOTATION :: NCX1&1&NUNX1&1&CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555369

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >12 gm/m3/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - excitement Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555369

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555369

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 16,367,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,146,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 16,367,1957

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 16,367,1957

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 16,367,1957 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg/11D-C

TOXIC EFFECTS :: Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555369 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84048 No. of Facilities: 63 (estimated) No. of Industries: 4 No. of Occupations: 7 No. of Employees: 640 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84048 No. of Facilities: 89 (estimated) No. of Industries: 7 No. of Occupations: 21 No. of Employees: 4313 (estimated) No. of Female Employees: 116 (estimated)

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H304-H315-H336-H361d-H373
Supplemental HS	Repeated exposure may cause skin dryness or cracking.
Precautionary Statements	P210-P261-P281-P301 + P310-P331
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	E;Xn
Risk Phrases	R2;R11;R20/22;R52/53
Safety Phrases	S39-S41-S47-S61
RIDADR	UN 3234 4.1
WGK Germany	2
RTECS	UG0800000
Packaging Group	II
Hazard Class	4.1
HS Code	2927000090

2-Amino-2-methy...

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2,2'-Azobis(2-m...

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Literature: US2713576 , ; DRP/DRBP Org.Chem. DE849109 , ; US2711405 , ;

Propionitrile, ...

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~99%

2,2'-Azobis(2-m...

CAS#:78-67-1

Literature: Tsubokawa; Takeda; Sone Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 11 p. 3541 - 3545

N-Hexadecyltrim...

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2-Amino-2-methy...

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~94%

2,2'-Azobis(2-m...

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Literature: E. I. Du Pont de Nemours and Company Patent: US4051124 A1, 1977 ;

Diazene,1,2-bis...

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Sodium cyanide

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2,2'-Azobis(2-m...

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Literature: Chimica, , vol. 13, p. 89 Justus Liebigs Annalen der Chemie, , vol. 631, p. 1,9

Propionitrile, ...

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benzene

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2,2'-Azobis(2-m...

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Literature: Justus Liebigs Annalen der Chemie, , vol. 566, p. 69,82

Propionitrile, ...

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benzene

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Benzoyl peroxide

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2,2'-Azobis(2-m...

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Literature: Justus Liebigs Annalen der Chemie, , vol. 566, p. 69,82

Precursor 7
CAS#:19355-69-2 2-Amino-2-methy... CAS#:6869-07-4 Propionitrile, ... CAS#:112-02-7 N-Hexadecyltrim... CAS#:29540-62-3 Diazene,1,2-bis...
CAS#:143-33-9 Sodium cyanide CAS#:71-43-2 benzene CAS#:94-36-0 Benzoyl peroxide
DownStream 10
CAS#:10551-67-4 2-methyl-2-(2-m... CAS#:3333-52-6 Tetramethylsucc... CAS#:78-82-0 Isobutyronitrile CAS#:84213-57-0 N-(1-Cyano-1-me...
CAS#:40517-43-9 4-(Methylsulfon... CAS#:542-76-7 3-chloropropion... CAS#:4300-97-4 Chloropivaloyl ... CAS#:3958-57-4 3-Nitrobenzyl b...
CAS#:14499-41-3 5,5-Diethoxy-2-... CAS#:10409-07-1 Disulfone,bis(4...

HS Code	2927000090
Summary	2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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2,2′-azobis(isobutyronitrile)

2,2-azobis(isobutyronitrile)

2,2'-[(E)-1,2-Diazenediyl]bis(2-methylpropanenitrile)

azobis(isobutyronitrile)

Propanenitrile, 2,2'-azobis[2-methyl-

2,2'-azobis-(2-methylpropionitrile)

2,2'-Azo-bis(isobutyronitrile)

Azodiisobutyrodinitrile

2,2'-Azobis(isobutyronitrile)

a,a'-azobis(isobutyronitrile)

azobisisobutyronitrile

EINECS 201-132-3

2,2'-Azobis[2-methylpropanenitrile]

KE-P 13

KB-P 13

Porofor-57

MFCD00013808

2,2'-azo-bis-isobutyronitrile

a,a'-azobisisobutyronitrile

azodiisobutyronitrile

azobisisobutironitrile

2,2'-azobis(isobutylonitrile)

VAZO 64

2,2'-Azodiisobutyronitrile

2,2'-Azobisisobutyronitrile

Propionitrile, 2,2'-azobis[2-methyl-

Vazo

2,2'-(E)-Diazene-1,2-diylbis(2-methylpropanenitrile)

AIBN

2,2′-azobis(2-methylpropionitrile)

2,2'-azo-bisisobutyronitrile

2,2′-azobisisobutyronitrile

2,2'-Azobis(2-methylpropionitrile)

a,a'-Azodiisobutyronitrile

Propanenitrile, 2,2'-[(E)-1,2-diazenediyl]bis[2-methyl-

Azo-bis-isobutyronitrile

α,α′-azobisisobutyronitrile

AIBN-64

2,2'-azobis-2-methylpropanenitrile

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China
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Price: ￥168.0/500g
Purity: 98.0%
Delivery: Inquiry
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Dayang Chem (Hangzhou) Co., Ltd.
China
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Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2,2'-Azobis(2-methylpropionitrile)
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
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2,2'-Azobis(2-methylpropionitrile)

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