SL 0101-1
Modify Date: 2024-01-02 11:30:44
SL 0101-1 structure
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Common Name | SL 0101-1 | ||
|---|---|---|---|---|
| CAS Number | 77307-50-7 | Molecular Weight | 516.451 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 753.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C25H24O12 | Melting Point | 128-132ºC | |
| MSDS | N/A | Flash Point | 255.6±26.4 °C | |
Use of SL 0101-1SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1]. |
| Name | Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside) |
|---|---|
| Synonym | More Synonyms |
| Description | SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1]. |
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| Related Catalog | |
| Target |
IC50: 89 nM (RSK)[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 753.0±60.0 °C at 760 mmHg |
| Melting Point | 128-132ºC |
| Molecular Formula | C25H24O12 |
| Molecular Weight | 516.451 |
| Flash Point | 255.6±26.4 °C |
| Exact Mass | 516.126770 |
| PSA | 182.19000 |
| LogP | 2.75 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.666 |
| Storage condition | -20℃ |
| Precursor 9 | |
|---|---|
| DownStream 1 | |
![5,7-Bis-(benzyloxy)-α-(4-(benzyloxy)phenyl)-3-[3,4-di-O-acetyl-α-O-acetyl-α-L-rhamnopyranosyloxyl]-4H-chromen-4-one Structure](https://www.chemsrc.com/caspic/064/849938-27-8.png)
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CAS#:482-39-3| 4H-1-Benzopyran-4-one, 3-[(3,4-di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
| 3',4'-Di-O-acetylafzelin |
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| SL 0101-1 |
| SL0101 |