Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-FLUOR-2-FENYL-9-METHYL-4-(PYRROLIDINE-1-CARBONYL)-9H-PYRIDO[3,4B]INDOOL-1(2H)-ON
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Purity: 98.0%
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205881-86-3

205881-86-3 structure

Name: SL-651,498
Chemical Name: 6-Fluoro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-2,9-dihydro -1H-β-carbolin-1-one
CAS Number: 205881-86-3
Molecular Formula: C₂₃H₂₀FN₃O₂
Molecular Weight: 389.42200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2018-06-11 17:35:20
Modify Date: 2025-08-21 12:17:58
SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].

Name	6-Fluoro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-2,9-dihydro -1H-β-carbolin-1-one

Description	SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68.