Erythromycin Thicyanate

Modify Date: 2024-01-02 08:02:39

Erythromycin Thicyanate Structure
Erythromycin Thicyanate structure
Common Name Erythromycin Thicyanate
CAS Number 7704-67-8 Molecular Weight 792.010
Density N/A Boiling Point 818.4ºC at 760 mmHg
Molecular Formula C38H68N2O13S Melting Point N/A
MSDS N/A Flash Point 448.8ºC

 Use of Erythromycin Thicyanate


Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].

 Names

Name Erythromycin thiocyanate
Synonym More Synonyms

 Erythromycin Thicyanate Biological Activity

Description Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].
Related Catalog
In Vitro Erythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively[1].
References

[1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.

[2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28.

 Chemical & Physical Properties

Boiling Point 818.4ºC at 760 mmHg
Molecular Formula C38H68N2O13S
Molecular Weight 792.010
Flash Point 448.8ºC
Exact Mass 791.436951
PSA 256.50000
LogP 2.18288

 Safety Information

HS Code 2941500000

 Synthetic Route

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Erythromycin Thicyanate Structure

Erythromycin Th...

CAS#:7704-67-8

Literature: EP2301945 A1, ; Page/Page column 10 ;

 Customs

HS Code 2941500000

 Synonyms

ErythroMycin Thiocyanate CGMP
ErythroMicyn thiocyanate
ERYTHROMYCIN THIOCYANATE CP2000
erythromycin thiocynante
ERYTHROMYCIN THIOCYANATE NOT LESS THAN 750 U OF ERYFHROMYCIN PER MG
erythromycin A thiocyanate
ERYTHROMYCIN THIOCYNATE
erythromycin thiocyanante