2-Iminobiotin hydrobromide
Modify Date: 2024-01-09 06:44:13
2-Iminobiotin hydrobromide structure
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Common Name | 2-Iminobiotin hydrobromide | ||
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| CAS Number | 76985-52-9 | Molecular Weight | 324.24 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H18BrN3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2-Iminobiotin hydrobromide2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2]. |
| Name | 2-Iminobiotin hydrobromide |
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| Description | 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2]. |
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| Related Catalog | |
| Target |
NO synthases[1] |
| In Vitro | Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control[1]. |
| References |
| Molecular Formula | C10H18BrN3O2S |
|---|---|
| Molecular Weight | 324.24 |