Thiorphan

Modify Date: 2024-01-02 14:54:58

Thiorphan Structure
Thiorphan structure
Common Name Thiorphan
CAS Number 76721-89-6 Molecular Weight 253.32
Density 1.2±0.1 g/cm3 Boiling Point 524.0±50.0 °C at 760 mmHg
Molecular Formula C12H15NO3S Melting Point 138-140ºC
MSDS Chinese USA Flash Point 270.7±30.1 °C

 Use of Thiorphan


Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].

 Names

Name 2-[(2-benzyl-3-sulfanylpropanoyl)amino]acetic acid
Synonym More Synonyms

 Thiorphan Biological Activity

Description Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].
Related Catalog
References

[1]. Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 524.0±50.0 °C at 760 mmHg
Melting Point 138-140ºC
Molecular Formula C12H15NO3S
Molecular Weight 253.32
Flash Point 270.7±30.1 °C
Exact Mass 253.077271
PSA 105.20000
LogP 1.37
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.577

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

N-[(RS)-2-Benzyl-3-mercaptopropanoyl]-glycine
DL-[N-(3-mercapto-2-benzylpropanoyl)]glycine
Glycine,N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-,(+-)
N-[(R,S)-3-mercapto-2-benzyl-propionyl]glycine
DL-Thiorphan
Tiorphan
(2-mercaptomethyl-3-phenyl-propionylamino)-acetic acid
Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (±)-
Glycine, N-[3-mercapto-1-oxo-2-(phenylmethyl)propyl]-
N-(2-Benzyl-3-sulfanylpropanoyl)glycine
DL-3-Mercapto-2-benzylpropanoylglycine
Prestwick_694
N-(3-mercapto-2-benzylpropanoyl)glycine
(2-MERCAPTOMETHYL-3-PHENYL-PROPIONYL)-GLYCINE
(3-Mercapto-2-benzylpropionyl)glycine
Thiorphan
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