ORM-10962

Modify Date: 2024-01-10 18:21:08

ORM-10962 structure	Common Name	ORM-10962
	CAS Number	763926-98-3	Molecular Weight	459.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₉N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ORM-10962

ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 values of 67 and 55 nM for the reverse and forward mode inhibition, respectively[1][2].

Name	ORM-10962

Description	ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 values of 67 and 55 nM for the reverse and forward mode inhibition, respectively[1][2].
Related Catalog	Research Areas >> Others
Target	NCX[1][2].
References	[1]. Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041. [2]. Oravecz K, et al. Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes. Eur J Pharmacol. 2018 Jan 5;818:278-286.

Molecular Formula	C₂₇H₂₉N₃O₄
Molecular Weight	459.54

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China
Product Name: ORM-10962
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ORM-10962

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