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ShangHai DC Chemicals Co.,Ltd
China
Product Name: ORM-10962
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DC Chemicals Limited
China
Product Name: ORM-10962
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Purity: 98.0%
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763926-98-3

763926-98-3 structure

763926-98-3 structure

Name: ORM-10962
Chemical Name: ORM-10962
CAS Number: 763926-98-3
Molecular Formula: C₂₇H₂₉N₃O₄
Molecular Weight: 459.54
Catalog: Research Areas Others
Create Date: 2019-06-30 20:11:15
Modify Date: 2024-01-10 18:21:08
ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 values of 67 and 55 nM for the reverse and forward mode inhibition, respectively[1][2].

Name	ORM-10962

Description	ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 values of 67 and 55 nM for the reverse and forward mode inhibition, respectively[1][2].
Related Catalog	Research Areas >> Others
Target	NCX[1][2].
References	[1]. Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041. [2]. Oravecz K, et al. Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes. Eur J Pharmacol. 2018 Jan 5;818:278-286.

Molecular Formula	C₂₇H₂₉N₃O₄
Molecular Weight	459.54

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