ARTOCARPIN

Modify Date: 2025-08-25 08:48:22

ARTOCARPIN Structure
ARTOCARPIN structure
Common Name ARTOCARPIN
CAS Number 7608-44-8 Molecular Weight 436.50
Density 1.2±0.1 g/cm3 Boiling Point 651.7±55.0 °C at 760 mmHg
Molecular Formula C26H28O6 Melting Point N/A
MSDS N/A Flash Point 219.9±25.0 °C

 Use of ARTOCARPIN


Artocarpin is an isoprenoid-substituted flavonoid, that can be isolated from the wood of Artocarpus heterophyllus. Artocarpin inhibits melanin biosynthesis in B16 melanoma cells without inhibiting tyrosinase. The presence of the isoprenoid-substituted moiety enhanced the inhibitory activity on melanin production in B16 melanoma cells[1].

 Names

Name 2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(1E)-3-methyl-1-bu ten-1-yl]-3-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
Synonym More Synonyms

 ARTOCARPIN Biological Activity

Description Artocarpin is an isoprenoid-substituted flavonoid, that can be isolated from the wood of Artocarpus heterophyllus. Artocarpin inhibits melanin biosynthesis in B16 melanoma cells without inhibiting tyrosinase. The presence of the isoprenoid-substituted moiety enhanced the inhibitory activity on melanin production in B16 melanoma cells[1].
Related Catalog
References

[1]. Arung ET, et al. Inhibitory effect of isoprenoid-substituted flavonoids isolated from Artocarpus heterophyllus on melanin biosynthesis. Planta Med. 2006 Jul;72(9):847-50.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 651.7±55.0 °C at 760 mmHg
Molecular Formula C26H28O6
Molecular Weight 436.50
Flash Point 219.9±25.0 °C
Exact Mass 436.188599
PSA 100.13000
LogP 6.35
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.614
InChIKey KRGDFVQWQJIMEK-RMKNXTFCSA-N
SMILES COc1cc2oc(-c3ccc(O)cc3O)c(CC=C(C)C)c(=O)c2c(O)c1C=CC(C)C

 Safety Information

Hazard Codes Xi

 Synthetic Route

 Synonyms

2-(2,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(1E)-3-methylbut-1-en-1-yl]-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Norartocarpin
ARTOCARPIN
2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-3,6-bis(3-methyl-2-buten-1-yl)-
2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-3,6-bis(3-methyl-2-buten-1-yl)-4H-chromen-4-one
2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(1E)-3-methyl-1-buten-1-yl]-3-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(1E)-3-methyl-1-buten-1-yl]-3-(3-methyl-2-buten-1-yl)-
Kuwanon C
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