Exo1

Modify Date: 2024-01-05 19:13:46

Exo1 Structure
Exo1 structure
Common Name Exo1
CAS Number 75541-83-2 Molecular Weight 273.25900
Density 1.298 g/cm3 Boiling Point 333.9ºC at 760 mmHg
Molecular Formula C15H12FNO3 Melting Point N/A
MSDS Chinese USA Flash Point 155.8ºC

 Use of Exo1


Exo1 is a chemical inhibitor of the exocytic pathway.

 Names

Name methyl 2-[(4-fluorobenzoyl)amino]benzoate
Synonym More Synonyms

 Exo1 Biological Activity

Description Exo1 is a chemical inhibitor of the exocytic pathway.
Related Catalog
In Vitro Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I[1].
References

[1]. Feng Y, et al. Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6469-74.

 Chemical & Physical Properties

Density 1.298 g/cm3
Boiling Point 333.9ºC at 760 mmHg
Molecular Formula C15H12FNO3
Molecular Weight 273.25900
Flash Point 155.8ºC
Exact Mass 273.08000
PSA 55.40000
LogP 2.93760
Storage condition 2-8℃

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

2-(4-Fluorobenzoylamino)benzoic acid methyl ester,2-(4-Fluorobenzoylamino)methylbenzoate
2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
2-(4-Fluoro-benzoylami
4-FLUORO-BZ-2-ABZ-OME
EOX 1
2-(2-METHOXY-BENZYL)-SUCCINIC ACID.
EXO1
EXOCYTIC INHIBITOR 1
2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
Exo1,Exocytic Inhibitor 1,2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Exo1
  • Price: $550.0/100mg $950.0/250mg $1800.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

  • Dayang Chem (Hangzhou) Co., Ltd.
  • China
  • Product Name: EXO1
  • Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
  • Purity: 98.0%
  • Stocking Period: Inquiry
  • Contact: Ms Wang

Get all suppliers and price by the below link:

Exo1 suppliers


Price: ¥660/10 mM * 1 mL in DMSO

Reference only. check more Exo1 price

Related Compounds: More...