75541-83-2
75541-83-2 structure
- Name: Exo1
- Chemical Name: methyl 2-[(4-fluorobenzoyl)amino]benzoate
- CAS Number: 75541-83-2
- Molecular Formula: C15H12FNO3
- Molecular Weight: 273.25900
- Catalog: Research Areas Others
- Create Date: 2016-02-19 15:25:52
- Modify Date: 2024-01-05 19:13:46
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Exo1 is a chemical inhibitor of the exocytic pathway.
| Name | methyl 2-[(4-fluorobenzoyl)amino]benzoate |
|---|---|
| Synonyms |
2-(4-Fluorobenzoylamino)benzoic acid methyl ester,2-(4-Fluorobenzoylamino)methylbenzoate
2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER 2-(4-Fluoro-benzoylami 4-FLUORO-BZ-2-ABZ-OME EOX 1 2-(2-METHOXY-BENZYL)-SUCCINIC ACID. EXO1 EXOCYTIC INHIBITOR 1 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE Exo1,Exocytic Inhibitor 1,2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester |
| Description | Exo1 is a chemical inhibitor of the exocytic pathway. |
|---|---|
| Related Catalog | |
| In Vitro | Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I[1]. |
| References |
| Density | 1.298 g/cm3 |
|---|---|
| Boiling Point | 333.9ºC at 760 mmHg |
| Molecular Formula | C15H12FNO3 |
| Molecular Weight | 273.25900 |
| Flash Point | 155.8ºC |
| Exact Mass | 273.08000 |
| PSA | 55.40000 |
| LogP | 2.93760 |
| Storage condition | 2-8℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |