4-Amidinophenylmethanesulfonyl fluoride hydrochloride

Modify Date: 2024-01-05 15:03:02

4-Amidinophenylmethanesulfonyl fluoride hydrochloride Structure
4-Amidinophenylmethanesulfonyl fluoride hydrochloride structure
Common Name 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
CAS Number 74938-88-8 Molecular Weight 252.69
Density N/A Boiling Point 405.2ºC at 760 mmHg
Molecular Formula C8H10ClFN2O2S Melting Point ~205 °C (dec.)
MSDS USA Flash Point 198.8ºC

 Use of 4-Amidinophenylmethanesulfonyl fluoride hydrochloride


p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1].

 Names

Name 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
Synonym More Synonyms

  Biological Activity

Description p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1].
Related Catalog
References

[1]. LauraR, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitorof serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64.  

 Chemical & Physical Properties

Boiling Point 405.2ºC at 760 mmHg
Melting Point ~205 °C (dec.)
Molecular Formula C8H10ClFN2O2S
Molecular Weight 252.69
Flash Point 198.8ºC
Exact Mass 252.013550
PSA 92.39000
LogP 3.45280
Storage condition −20°C
Water Solubility H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases 20/21/22-36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925290090

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

(4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
(4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride (1:1)
Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-, hydrochloride (1:1)
(4-carbamimidoylphenyl)methanesulfonyl fluoride,hydrochloride
MFCD00036898
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  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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