Bisdionin C
Modify Date: 2025-08-25 17:17:55
Bisdionin C structure
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Common Name | Bisdionin C | ||
|---|---|---|---|---|
| CAS Number | 74857-22-0 | Molecular Weight | 400.39200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H20N8O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Bisdionin CBisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1]. |
| Name | 1,1'-trimethylenebis[theobromine] |
|---|---|
| Synonym | More Synonyms |
| Description | Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
GH18 Chitinases[1] |
| References |
| Molecular Formula | C17H20N8O4 |
|---|---|
| Molecular Weight | 400.39200 |
| Exact Mass | 400.16100 |
| PSA | 123.64000 |
| InChIKey | KEPIKAFUZRKZMT-UHFFFAOYSA-N |
| SMILES | Cn1cnc2c1c(=O)n(CCCn1c(=O)c3c(ncn3C)n(C)c1=O)c(=O)n2C |
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| 1,3-Bis-[theobrominyl-(1)]-propan |
| bisdionin C |
| 3,7,3',7'-tetramethyl-3,7,3',7'-tetrahydro-1,1'-propane-1,3-diyl-bis-purine-2,6-dione |