Methylophiopogonanone B

Modify Date: 2024-01-02 17:25:14

Methylophiopogonanone B structure	Common Name	Methylophiopogonanone B
	CAS Number	74805-91-7	Molecular Weight	328.359
	Density	1.285	Boiling Point	554.5±49.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₀O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	201.5±23.3 °C

Use of Methylophiopogonanone B

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

Name	(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
Synonym	More Synonyms

Description	Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Ras
References	[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root. [2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> Ras

References

[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.

[2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Density	1.285
Boiling Point	554.5±49.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₀O₅
Molecular Weight	328.359
Flash Point	201.5±23.3 °C
Exact Mass	328.131073
PSA	75.99000
LogP	5.22
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.617