<Suppliers Price>

Methylophiopogonanone B

Names

[ CAS No. ]:
74805-91-7

[ Name ]:
Methylophiopogonanone B

[Synonym ]:
methylophiopogonanone B
Methyl o-nitrophenylacetate
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-, (3R)-
2-nitrophenylacetic acid methyl ester
(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one

Biological Activity

[Description]:

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> Ras

[References]

[1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.

[2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.

Chemical & Physical Properties

[ Density]:
1.285

[ Boiling Point ]:
554.5±49.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20O5

[ Molecular Weight ]:
328.359

[ Flash Point ]:
201.5±23.3 °C

[ Exact Mass ]:
328.131073

[ PSA ]:
75.99000

[ LogP ]:
5.22

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.617

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds