Imipenem
Modify Date: 2024-01-02 00:01:14
Imipenem structure
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Common Name | Imipenem | ||
|---|---|---|---|---|
| CAS Number | 74431-23-5 | Molecular Weight | 317.36 | |
| Density | 1.02 g/mL at 25 °C | Boiling Point | 34.6°C | |
| Molecular Formula | C12H19N3O5S | Melting Point | -116.3°C | |
| MSDS | USA | Flash Point | <−30 °F | |
Use of ImipenemImipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3]. |
| Name | imipenem hydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3]. |
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| Related Catalog | |
| References |
[2]. Jacoby GA, et al. AmpC beta-lactamases. Clin Microbiol Rev. 2009 Jan;22(1):161-82. |
| Density | 1.02 g/mL at 25 °C |
|---|---|
| Boiling Point | 34.6°C |
| Melting Point | -116.3°C |
| Molecular Formula | C12H19N3O5S |
| Molecular Weight | 317.36 |
| Flash Point | <−30 °F |
| Exact Mass | 317.104553 |
| PSA | 148.25000 |
| LogP | 0.18820 |
| Storage condition | -20°C Freezer |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | F+,C,F |
| Risk Phrases | R12:Extremely Flammable. R14/15:Reacts violently with water, liberating extremely flammable gases . R19:May form explosive peroxides. R22:Harmful if swallowed. R34:Causes burns. R66:Repeated exposure may cause skin dryness or cracking. R67:Vapors may cause |
| Safety Phrases | S16-S26-S36/37/39-S43-S45-S7/8-S27 |
| RIDADR | UN 3399 4.3/PG 1 |
| WGK Germany | 1 |
| Packaging Group | I |
| Hazard Class | 4.3 |
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Combined disc methods for the detection of KPC- and/or VIM-positive Klebsiella pneumoniae: improving reliability for the double carbapenemase producers.
Clin. Microbiol. Infect. 19(9) , E412-5, (2013) Klebsiella pneumoniae strains co-producing klebsiella pneumoniae carbapenemase (KPC) and verona integron-encoded metallo-beta-lactamase (VIM) are frequently isolated in Greece and have also occurred i... |
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Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes.
Biol. Pharm. Bull. 38 , 1425-9, (2015) The direct inhibitory potential of twenty five anti-tuberculosis drugs on eight CYP-specific reactions in human liver microsomes was investigated to predict in vivo drug-drug interactions (DDIs) from ... |
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Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance.
J. Antimicrob. Chemother. 70 , 1434-42, (2015) Colistin is an 'old' drug, which is being increasingly utilized due to limited therapeutic options. However, resistance emergence during monotherapy is concerning. Here, our objective was to optimize ... |
| 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, hydrate (1:1) |
| (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid monohydrate |
| (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäurehydrat |
| (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1) |
| Imipenem hydrate |
| N-Formimidoylthienamycin Monohydrate |
| MFCD08458212 |
| Imipenem monohydrate |
| Imipenem, Monohydrate |
| EINECS 264-734-5 |
| 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, monohydrate |
| acide (5R,6S)-6-[(1R)-1-hydroxyéthyl]-3-({2-[(iminométhyl)amino]éthyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ène-2-carboxylique hydrate |
| [5R-[5a,6a(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Monohydrate |
| (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate |
| Imipenem |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Imipenem
- Price: ￥498.0/100mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Primaxin hydrate
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Imipenem
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Imipenem
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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