Schnurri-3 inhibitor-1

Modify Date: 2024-04-08 16:40:48

Schnurri-3 inhibitor-1 Structure
Schnurri-3 inhibitor-1 structure
Common Name Schnurri-3 inhibitor-1
CAS Number 736154-60-2 Molecular Weight 284.28
Density N/A Boiling Point N/A
Molecular Formula C12H10F2N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Schnurri-3 inhibitor-1


Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1].

 Names

Name Benzenesulfonamide, 3,4-difluoro-N-(4-pyridinylmethyl)-

 Schnurri-3 inhibitor-1 Biological Activity

Description Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1].
Related Catalog
Target

Schnurri-3[1]

In Vitro Schnurri-3 inhibitor-1 (0-50 μM; 24 h) can inhibit Shn3 with EF1alpha promoter in SV40 large T antigen-transformed osteoblast cell line (Clone20-Shn3FFL) with an AC50 value of 2.09 μM[1]. Schnurri-3 inhibitor-1 (0.195-26 μM; 48 h) exhibits moderate activity in HepG2 mammalian cells with an AC50 value of 54.73 μM[1]. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 2.09 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 2.09 μM. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 1.2 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 1.2 μM.
References

[1]. National Center for Biotechnology Information. PubChem Compound Summary for CID 2473445.

 Chemical & Physical Properties

Molecular Formula C12H10F2N2O2S
Molecular Weight 284.28