6-Iodoacetamidofluorescein

Modify Date: 2024-01-02 13:15:46

6-Iodoacetamidofluorescein Structure
6-Iodoacetamidofluorescein structure
Common Name 6-Iodoacetamidofluorescein
CAS Number 73264-12-7 Molecular Weight 515.25400
Density 1.95g/cm3 Boiling Point 798.5ºC at 760 mmHg
Molecular Formula C22H14INO6 Melting Point N/A
MSDS USA Flash Point 436.7ºC

 Use of 6-Iodoacetamidofluorescein


6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins[1][2].

 Names

Name N-(3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-yl)-2-iodoacetamide
Synonym More Synonyms

 6-Iodoacetamidofluorescein Biological Activity

Description 6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins[1][2].
Related Catalog
References

[1]. Martelli AM, et, al. Probing the sulfhydryl groups of nuclear matrix proteins with 6-iodoacetamidofluorescein. Cell Biol Int Rep. 1990 May;14(5):409-18.

[2]. Cocco L, et, al. Changes in nucleosome structure and histone H3 accessibility. Iodoacetamidofluorescein labelling after treatment with phosphatidylserine vesicles. Exp Cell Res. 1986 Oct;166(2):465-74.

 Chemical & Physical Properties

Density 1.95g/cm3
Boiling Point 798.5ºC at 760 mmHg
Molecular Formula C22H14INO6
Molecular Weight 515.25400
Flash Point 436.7ºC
Exact Mass 514.98700
PSA 105.09000
LogP 4.11230
Index of Refraction 1.813

 Safety Information

RIDADR NONH for all modes of transport

 Articles11

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Identification and localization of the 5-iodoacetamido-fluorescein reporter site on dog kidney Na,K-ATPase.

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Methods Mol. Biol. 211 , 333-54, (2003)

Clozapine causes oxidation of proteins involved in energy metabolism: a possible mechanism for antipsychotic-induced metabolic alterations.

Int. J. Neuropsychopharmacol. 11(8) , 1097-104, (2008)

Although atypical antipsychotics are widely known to induce alterations in lipid and glucose metabolism, the mechanisms by which these alterations occur remain unknown. Several recent studies have sho...

 Synonyms

6-IAF
6-Iodoacetamidofluorescein
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