6-Iodoacetamidofluorescein

Names

[ Name ]:
6-Iodoacetamidofluorescein

[Synonym ]:
6-IAF
6-Iodoacetamidofluorescein

Biological Activity

[Description]:

6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Martelli AM, et, al. Probing the sulfhydryl groups of nuclear matrix proteins with 6-iodoacetamidofluorescein. Cell Biol Int Rep. 1990 May;14(5):409-18.

[2]. Cocco L, et, al. Changes in nucleosome structure and histone H3 accessibility. Iodoacetamidofluorescein labelling after treatment with phosphatidylserine vesicles. Exp Cell Res. 1986 Oct;166(2):465-74.

Chemical & Physical Properties

[ Density]:
1.95g/cm3

[ Boiling Point ]:
798.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₂H₁₄INO₆

[ Molecular Weight ]:
515.25400

[ Flash Point ]:
436.7ºC

[ Exact Mass ]:
514.98700

[ PSA ]:
105.09000

[ LogP ]:
4.11230

[ Index of Refraction ]:
1.813

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Identification and localization of the 5-iodoacetamido-fluorescein reporter site on dog kidney Na,K-ATPase.

Prog. Clin. Biol. Res. 273 , 39-44, (1988)

Chemical modifications of proteins as an aid to sequence analysis.

Methods Mol. Biol. 211 , 333-54, (2003)

Clozapine causes oxidation of proteins involved in energy metabolism: a possible mechanism for antipsychotic-induced metabolic alterations.

Int. J. Neuropsychopharmacol. 11(8) , 1097-104, (2008)

Although atypical antipsychotics are widely known to induce alterations in lipid and glucose metabolism, the mechanisms by which these alterations occur remain unknown. Several recent studies have sho...