3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester

Modify Date: 2025-08-25 15:33:16

3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester structure	Common Name	3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester
	CAS Number	72506-14-0	Molecular Weight	402.57
	Density	1.1±0.1 g/cm3	Boiling Point	501.0±50.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₃₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	158.5±23.6 °C

Use of 3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester

Vibsanin A, a protein kinase C (PKC) activator, exhibits anti-proliferative activity against human cancer cell lines. Vibsanin A is also a HSP90 inhibitor[1].

Name	(1R,2R,5S,7E,11R)-8-(Hydroxymethyl)-1,5-dimethyl-5-(4-methyl-3-penten-1-yl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl 3-methyl-2-butenoate
Synonym	More Synonyms

Description	Vibsanin A, a protein kinase C (PKC) activator, exhibits anti-proliferative activity against human cancer cell lines. Vibsanin A is also a HSP90 inhibitor[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP Signaling Pathways >> TGF-beta/Smad >> PKC
References	[1]. Miura K, et, al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253. [2]. Shen X, et, al. Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn. Biochem Biophys Res Commun. 2018 Jul 7;502(1):110-115.

Description

Vibsanin A, a protein kinase C (PKC) activator, exhibits anti-proliferative activity against human cancer cell lines. Vibsanin A is also a HSP90 inhibitor[1].

Related Catalog

Signaling Pathways >> Epigenetics >> PKC

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP

Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

Signaling Pathways >> TGF-beta/Smad >> PKC

References

[1]. Miura K, et, al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.

[2]. Shen X, et, al. Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn. Biochem Biophys Res Commun. 2018 Jul 7;502(1):110-115.

Density	1.1±0.1 g/cm3
Boiling Point	501.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₈O₄
Molecular Weight	402.57
Flash Point	158.5±23.6 °C
Exact Mass	402.277008
LogP	7.24
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.528
InChIKey	FUGMARDYCOVINL-UHHANTDWSA-N
SMILES	CC(C)=CCCC1(C)C=CC(OC(=O)C=C(C)C)C2(C)OC2CCC(CO)=CC1

2-Butenoic acid, 3-methyl-, (1R,2R,5S,7E,11R)-8-(hydroxymethyl)-1,5-dimethyl-5-(4-methyl-3-penten-1-yl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl ester

2-Butenoic acid, 3-methyl-, (1R,2R,3E,5S,7E,11R)-8-(hydroxymethyl)-1,5-dimethyl-5-(4-methyl-3-penten-1-yl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl ester

(1R,2R,5S,7E,11R)-8-(Hydroxymethyl)-1,5-dimethyl-5-(4-methyl-3-penten-1-yl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl 3-methyl-2-butenoate

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3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester

Use of 3-Methyl-2-butenoic acid [8-hydroxymethyl-1,5-dimethyl-5-(4-methyl-3-pentenyl)-12-oxabicyclo[9.1.0]dodeca-3,7-dien-2-yl] ester

Names

Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.