1,4-Bis(3-aminopropyl)piperazine

Modify Date: 2025-08-22 09:46:52

1,4-Bis(3-aminopropyl)piperazine Structure
1,4-Bis(3-aminopropyl)piperazine structure
Common Name 1,4-Bis(3-aminopropyl)piperazine
CAS Number 7209-38-3 Molecular Weight 200.324
Density 1.0±0.1 g/cm3 Boiling Point 334.5±0.0 °C at 760 mmHg
Molecular Formula C10H24N4 Melting Point 15 °C(lit.)
MSDS Chinese USA Flash Point 162.8±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 1,4-Bis(3-aminopropyl)piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 334.5±0.0 °C at 760 mmHg
Melting Point 15 °C(lit.)
Molecular Formula C10H24N4
Molecular Weight 200.324
Flash Point 162.8±0.0 °C
Exact Mass 200.200104
PSA 58.52000
LogP -1.43
Vapour density 6.9 (vs air)
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.505

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S27-S28-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 3
RTECS TK8700000
Packaging Group II
Hazard Class 8
HS Code 2933599090

 Synthetic Route

~10%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: ARGENTA DISCOVERY LTD Patent: WO2006/82412 A2, 2006 ; Location in patent: Page/Page column 78 ; WO 2006/082412 A2

~97%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: Sogang University Research Foundation; HUR, Nam Hwi; LEE, Byeong No Patent: US2014/51858 A1, 2014 ; Location in patent: Paragraph 0081-0082 ;

~%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: Journal of the American Chemical Society, , vol. 68, p. 1296

~%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: Journal of the American Chemical Society, , vol. 68, p. 1296

~79%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: Bernard, Helene; Del Rio Garcia, Eugenia; Ferec, Sonia; Kervarec, Nelly; Handel, Henri European Journal of Organic Chemistry, 2003 , # 2 p. 255 - 258

~%

1,4-Bis(3-aminopropyl)piperazine Structure

1,4-Bis(3-amino...

CAS#:7209-38-3

Literature: European Journal of Organic Chemistry, , # 6 p. 1050 - 1055

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Multifunctional disulfide-based cationic dextran conjugates for intravenous gene delivery targeting ovarian cancer cells.

Mol. Pharm. 11(7) , 2250-61, (2014)

A folate-decorated, disulfide-based cationic dextran conjugate having dextran as the main chain and disulfide-linked 1,4-bis(3-aminopropyl)piperazine (BAP) residues as the grafts was designed and succ...

Thermodynamic Investigation and Mixed Ligand Complex Formation of 1,4-Bis-(3-aminopropyl)-piperazine and Biorelevant Ligands.

Bioinorg. Chem. Appl. 2012 , 984291, (2012)

Thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) and its metal complexation with some divalent metal ions were determined in aqueous solution at constant ionic stre...

Multifunctional cationic polyurethanes designed for non-viral cancer gene therapy.

Acta Biomater. 30 , 155-67, (2015)

Nano-polyplexes from bioreducible cationic polymers have a massive promise for cancer gene therapy. However, the feasibility of cationic polyurethanes for non-viral gene therapy is so far not well stu...

 Synonyms

MFCD00006161
1,4-Piperazinedipropanamine
3,3'-(1,4-Piperazinediyl)di(1-propanamine)
EINECS 230-589-1
1,4-Bis(3-aminopropyl)piperazine
3,3'-PIPERAZINE-1,4-DIYLDIPROPAN-1-AMINE
BAPPRZ
BIS AMINOPROPYL PIPIRAZINE
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