2-Phenyl-6,7-dimethylquinoxaline

Modify Date: 2025-08-25 10:00:52

2-Phenyl-6,7-dimethylquinoxaline Structure
2-Phenyl-6,7-dimethylquinoxaline structure
 Common Name 2-Phenyl-6,7-dimethylquinoxaline
CAS Number 71897-07-9 Molecular Weight 234.296
Density 1.1±0.1 g/cm3 Boiling Point 398.3±37.0 °C at 760 mmHg
Molecular Formula C16H14N2 Melting Point N/A
MSDS N/A Flash Point 172.4±17.8 °C

 Use of 2-Phenyl-6,7-dimethylquinoxaline


AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].

 Names

Name 6,7-dimethyl-2-phenylquinoxaline
Synonym More Synonyms

 2-Phenyl-6,7-dimethylquinoxaline Biological Activity

Description AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].
Related Catalog
Target

PDGFR[1]

References

[1]. Zheng Y, et al. Platelet-derived growth factor receptor kinase inhibitor AG1295 and inhibition of experimental proliferative vitreoretinopathy. Jpn J Ophthalmol. 2003 Mar-Apr;47(2):158-65.

[2]. Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295. Transplantation. 2002 Nov 15;74(9):1335-41.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 398.3±37.0 °C at 760 mmHg
Molecular Formula C16H14N2
Molecular Weight 234.296
Flash Point 172.4±17.8 °C
Exact Mass 234.115692
PSA 25.78000
LogP 3.92
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.636
InChIKey FQNCLVJEQCJWSU-UHFFFAOYSA-N
SMILES Cc1cc2ncc(-c3ccccc3)nc2cc1C
Storage condition −20°C

 Safety Information

Safety Phrases S22;S24/25
WGK Germany 3
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

AG 1295
2-Phenyl-6,7-dimethylquinoxaline
F1284-0835
TYRPHOSTIN AG 1295
6,7-Dimethyl-2-phenylquinoxaline
6,7-dimethyl-2-phenyl-quinoxaline
Quinoxaline, 6,7-dimethyl-2-phenyl-
6,7-Dimethyl-2-phenyl-chinoxalin
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