(R)-Mephenytoin

Modify Date: 2024-01-05 11:29:03

(R)-Mephenytoin structure	Common Name	(R)-Mephenytoin
	CAS Number	71140-51-7	Molecular Weight	218.25200
	Density	1.154g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₄N₂O₂	Melting Point	137-138ºC
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of (R)-Mephenytoin

(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2].

Name	(R)-Mephenytoin
Synonym	More Synonyms

Description	(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease
In Vitro	(R)-Mephenytoin can be N-demethylated by the cytochrome P450 (CYP) isoform CYP2C9 to form the metabolite 5-phenyl-5-ethylhydantoin (nirvanol)[1].
References	[1]. Meier UT, et, al. Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography. Anal Biochem. 1985 Dec;151(2):286-91. [2]. Relling MV, et, al. Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily. J Pharmacol Exp Ther. 1990 Jan;252(1):442-7.

Density	1.154g/cm3
Melting Point	137-138ºC
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25200
Exact Mass	218.10600
PSA	49.41000
LogP	1.74020
Index of Refraction	1.541

(R)-Mephenytoin MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport

(r)-(-)-mephenytoin

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (R)-Mephenytoin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,1,3-BENZOXADIAZOLE-4-SULFONAMIDE,7-(3-AMINO-1-PYRROLIDINYL)-N,N-DIMETHYL-,(S)-(9CI)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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