Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone

Modify Date: 2025-08-20 22:54:00

Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone Structure
Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone structure
Common Name Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone
CAS Number 6971-97-7 Molecular Weight 277.14900
Density 1.21g/cm3 Boiling Point 387.794ºC at 760 mmHg
Molecular Formula C14H10Cl2N2 Melting Point N/A
MSDS Chinese USA Flash Point 188.331ºC
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

 Use of Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone


DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].

 Names

Name DCB,[(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde
Synonym More Synonyms

  Biological Activity

Description DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].
Related Catalog
Target

mGluR 5

References

[1]. O'Brien JA, et al. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol Pharmacol. 2003; 64(3):731-40.

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 387.794ºC at 760 mmHg
Molecular Formula C14H10Cl2N2
Molecular Weight 277.14900
Flash Point 188.331ºC
Exact Mass 276.02200
PSA 24.72000
LogP 4.44640
Index of Refraction 1.59
InChIKey XMOVWXSCYLINBJ-UHFFFAOYSA-N
SMILES Clc1cccc(C=NN=Cc2cccc(Cl)c2)c1

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H302-H315-H317-H318-H335-H410
Precautionary Statements P261-P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn,N
Risk Phrases 22-37/38-41-43-50/53
Safety Phrases 26-36/37-60-61
RIDADR UN 3077 9/PG 3

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 Synonyms

Benzaldehyde,m-chloro-,azine
3,3'-Dichlor-benzaldorzin
3.3'-Dichlor-benzaldazin
3,3'-DICHLOROBENZALDAZINE
3,3'-Dichlorobenzylideneazine
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