Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone

Modify Date: 2024-01-03 17:17:23

Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone Structure
Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone structure
Common Name Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone
CAS Number 6971-97-7 Molecular Weight 277.14900
Density 1.21g/cm3 Boiling Point 387.794ºC at 760 mmHg
Molecular Formula C14H10Cl2N2 Melting Point N/A
MSDS Chinese USA Flash Point 188.331ºC
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

 Use of Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone


DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].

 Names

Name DCB,[(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde
Synonym More Synonyms

  Biological Activity

Description DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].
Related Catalog
Target

mGluR 5

References

[1]. O'Brien JA, et al. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol Pharmacol. 2003; 64(3):731-40.

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 387.794ºC at 760 mmHg
Molecular Formula C14H10Cl2N2
Molecular Weight 277.14900
Flash Point 188.331ºC
Exact Mass 276.02200
PSA 24.72000
LogP 4.44640
Index of Refraction 1.59

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H302-H315-H317-H318-H335-H410
Precautionary Statements P261-P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn,N
Risk Phrases 22-37/38-41-43-50/53
Safety Phrases 26-36/37-60-61
RIDADR UN 3077 9/PG 3

 Articles13

More Articles
Solution processed organic photodetector utilizing an interdiffused polymer/fullerene bilayer.

Opt. Express 23 , A936-46, (2015)

Low dark current (off-current) and high photo current are both essential for a solution processed organic photodetector (OPD) to achieve high photo-responsivity. Currently, most OPDs utilize a bulk he...

3D intra-stacked CoO/carbon nanocomposites welded by Ag nanoparticles for high-capacity, reversible lithium storage.

Nanoscale 7 , 10368-76, (2015)

A wet-chemical, facile strategy is proposed for forming three-dimensional intra-structured nanocomposites to facilitate the development of high performance anodes for lithium ion batteries. The nanoco...

In vitro evaluation of paclitaxel coatings for delivery via drug-coated balloons.

Eur. J. Pharm. Biopharm. 96 , 322-8, (2015)

Lately, drug-coated balloons have been introduced in interventional cardiology as an approach to treat occluded blood vessel. They were developed for the rapid transfer of antiproliferative drugs duri...

 Synonyms

Benzaldehyde,m-chloro-,azine
3,3'-Dichlor-benzaldorzin
3.3'-Dichlor-benzaldazin
3,3'-DICHLOROBENZALDAZINE
3,3'-Dichlorobenzylideneazine
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: DCB
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


Get all suppliers and price by the below link:

Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone suppliers

Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3