6971-97-7

6971-97-7 structure

Name: Benzaldehyde,3-chloro-, 2-[(3-chlorophenyl)methylene]hydrazone
Chemical Name: DCB,[(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde
CAS Number: 6971-97-7
Molecular Formula: C₁₄H₁₀Cl₂N₂
Molecular Weight: 277.14900
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2018-12-22 13:33:11
Modify Date: 2024-01-03 17:17:23
DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].

Name	DCB,[(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde
Synonyms	Benzaldehyde,m-chloro-,azine 3,3'-Dichlor-benzaldorzin 3.3'-Dichlor-benzaldazin 3,3'-DICHLOROBENZALDAZINE 3,3'-Dichlorobenzylideneazine

Description	DCB (3,3′-dichlorobenzaldazine) is an neutral allosteric modulator of themetabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5) . DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR 5
References	[1]. O'Brien JA, et al. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol Pharmacol. 2003; 64(3):731-40.

Symbol	GHS05, GHS07, GHS09
Signal Word	Danger
Hazard Statements	H302-H315-H317-H318-H335-H410
Precautionary Statements	P261-P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn,N
Risk Phrases	22-37/38-41-43-50/53
Safety Phrases	26-36/37-60-61
RIDADR	UN 3077 9/PG 3