Tos-PEG2-THP

Modify Date: 2024-03-16 13:24:54

Tos-PEG2-THP Structure
Tos-PEG2-THP structure
Common Name Tos-PEG2-THP
CAS Number 69502-32-5 Molecular Weight 344.42
Density N/A Boiling Point N/A
Molecular Formula C16H24O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG2-THP


Tos-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tos-PEG2-THP

 Tos-PEG2-THP Biological Activity

Description Tos-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H24O6S
Molecular Weight 344.42