Glycine-13C2

Modify Date: 2024-01-09 18:37:22

Glycine-13C2 Structure
Glycine-13C2 structure
Common Name Glycine-13C2
CAS Number 67836-01-5 Molecular Weight 77.052
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula 13C2H5NO2 Melting Point 240ºC (dec.)(lit.)
MSDS USA Flash Point N/A

 Use of Glycine-13C2


Glycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

 Names

Name 2-aminoacetic acid
Synonym More Synonyms

 Glycine-13C2 Biological Activity

Description Glycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 240ºC (dec.)(lit.)
Molecular Formula 13C2H5NO2
Molecular Weight 77.052
Exact Mass 77.038734
PSA 63.32000
Index of Refraction 1.461

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

1,2-<13C>-glycine
Glycine-C
[13C2]-glycine
MFCD00037549
(C)Glycine
<1,2-14C2>glycine
<1,2-13C2>glycine
doubly labeled glycine