Glycine-13C2

Names

[ Name ]:
Glycine-13C2

[Synonym ]:
1,2-<13C>-glycine
Glycine-C
[13C2]-glycine
MFCD00037549
(C)Glycine
<1,2-14C2>glycine
<1,2-13C2>glycine
doubly labeled glycine

Biological Activity

[Description]:

Glycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
240ºC (dec.)(lit.)

[ Molecular Formula ]:
₁₃C₂H₅NO₂

[ Molecular Weight ]:
77.052

[ Exact Mass ]:
77.038734

[ PSA ]:
63.32000

[ Index of Refraction ]:
1.461

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3