D-phenylalanine

Modify Date: 2024-01-02 15:25:03

D-phenylalanine Structure
D-phenylalanine structure
Common Name D-phenylalanine
CAS Number 673-06-3 Molecular Weight 165.189
Density 1.2±0.1 g/cm3 Boiling Point 307.5±30.0 °C at 760 mmHg
Molecular Formula C9H11NO2 Melting Point 273-276 °C(lit.)
MSDS USA Flash Point 139.8±24.6 °C

 Use of D-phenylalanine


D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].

 Names

Name D-phenylalanine
Synonym More Synonyms

 D-phenylalanine Biological Activity

Description D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].
Related Catalog
References

[1]. Li E, et al. D-Phenylalanine inhibits biofilm development of a marine microbe, Pseudoalteromonas sp. SC2014. FEMS Microbiol Lett. 2016 Sep;363(18).

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 307.5±30.0 °C at 760 mmHg
Melting Point 273-276 °C(lit.)
Molecular Formula C9H11NO2
Molecular Weight 165.189
Flash Point 139.8±24.6 °C
Exact Mass 165.078979
PSA 63.32000
LogP 1.11
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.576
Water Solubility 27 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY7533000
CHEMICAL NAME :
Alanine, phenyl-, D-
CAS REGISTRY NUMBER :
673-06-3
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H11-N-O2
MOLECULAR WEIGHT :
165.21
WISWESSER LINE NOTATION :
QVYZ1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
500 mg/kg/5W-I
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 1(3),124,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5452 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5535 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 307 (estimated) No. of Female Employees: 251 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R34
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AY7533000
HS Code 29224995

 Synthetic Route

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles19

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Bioorg. Med. Chem. 16 , 3530-6, (2008)

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 Synonyms

(S)-phenylalanine
L-Phenylalanine
H-D-Phe-OH
(2S)-2-amino-3-phenylpropanoic acid
L-PHENYLALININE
α-Amino-β-phenylpropionic acid, L-
H-Phe-OH
Alanine, 3-phenyl-
L-phenylalanine zwitterion
S-phenylalanine
D-b-Phenylalanine
D-β-Phenylalanine
(S)-(-)-Phenylalanine
(R)-Phenylalanine
(S)-a-Amino-b-phenylpropionic Acid
Alanine, phenyl-, L-
L-2-Amino-3-phenylpropionic acid
(S)-2-Amino-3-phenylpropionic acid
(S)-2-Amino-3-phenylpropanoic acid
D-a-Amino-b-phenylpropionic Acid
C6H5CH2CH(NH2)COOH
(S)-a-Aminohydrocinnamic Acid
D-α-Amino-β-phenylpropionic acid
Phenylalanine
α-Aminohydrocinnamic acid, L-
(L)-Phenylalanine
Phenylalanine (VAN)
Phenylalanine, L-
phenylalanine D-form
Benzenepropanoic acid, α-amino-, (S)-
l-Phe
EINECS 211-603-5
PhE
D-phenylalanine zwitterion
β-phenyl-L-alanine
d-Phe
(-)-Phenylalanine
(S)-α-Aminobenzenepropanoic acid
MFCD00004270
(R)-(+)-Phenylalanine
α-Amino-β-phenylpropionic acid
(2R)-2-amino-3-phenylpropanoic acid
(S)-A-Aminobenzenepropanoic Acid
D-Phenylalanine
D-alpha-Amino-beta-phenylpropionic acid
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