Acyclovir monophosphate

Modify Date: 2024-01-03 19:53:33

Acyclovir monophosphate structure	Common Name	Acyclovir monophosphate
	CAS Number	66341-16-0	Molecular Weight	305.185
	Density	2.1±0.1 g/cm3	Boiling Point	716.0±70.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₂N₅O₆P	Melting Point	>400ºC
	MSDS	N/A	Flash Point	386.8±35.7 °C

Use of Acyclovir monophosphate

Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].

Name	Acyclovir Monophosphate
Synonym	More Synonyms

Description	Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
References	[1]. Yao J, et al. Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. J Control Release. 2013 Sep 28;170(3):414-20. [2]. Elion GB, et al. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> HSV

Research Areas >> Infection

References

[1]. Yao J, et al. Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. J Control Release. 2013 Sep 28;170(3):414-20.

[2]. Elion GB, et al. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13.

Density	2.1±0.1 g/cm3
Boiling Point	716.0±70.0 °C at 760 mmHg
Melting Point	>400ºC
Molecular Formula	C₈H₁₂N₅O₆P
Molecular Weight	305.185
Flash Point	386.8±35.7 °C
Exact Mass	305.052521
PSA	175.39000
LogP	-2.21
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.780

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

6H-Purin-6-one, 2-amino-3,9-dihydro-9-[[2-(phosphonooxy)ethoxy]methyl]-

Acyclovir monophosphate

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China
Product Name: Acyclovir monophosphate
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Acyclovir monophosphate

Use of Acyclovir monophosphate

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Acyclovir monophosphate Biological Activity

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