66341-16-0

66341-16-0 structure

Name: Acyclovir monophosphate
Chemical Name: Acyclovir Monophosphate
CAS Number: 66341-16-0
Molecular Formula: C₈H₁₂N₅O₆P
Molecular Weight: 305.185
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2017-04-08 21:08:41
Modify Date: 2024-01-03 19:53:33
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].

Name	Acyclovir Monophosphate
Synonyms	2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate 6H-Purin-6-one, 2-amino-3,9-dihydro-9-[[2-(phosphonooxy)ethoxy]methyl]- Acyclovir monophosphate

Description	Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
References	[1]. Yao J, et al. Turning an antiviral into an anticancer drug: nanoparticle delivery of acyclovir monophosphate. J Control Release. 2013 Sep 28;170(3):414-20. [2]. Elion GB, et al. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13.