Protectin D1

Modify Date: 2026-07-31 20:58:12

Protectin D1 Structure
Protectin D1 structure
Common Name Protectin D1
CAS Number 660430-03-5 Molecular Weight 360.48700
Density N/A Boiling Point N/A
Molecular Formula C22H32O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Protectin D1


Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models[1][2].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name protectin D1
Synonym More Synonyms

 Protectin D1 Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Tungen JE, et al. Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents. Org Biomol Chem. 2018;16(36):6818-6823.

[2]. Serhan CN, et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes [published correction appears in J Immunol. 2006 Mar 15;176(6):3843]. J Immunol. 2006;176(3):1848-1859.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C22H32O4
Molecular Weight 360.48700
Exact Mass 360.23000
PSA 77.76000
LogP 4.49050
InChIKey CRDZYJSQHCXHEG-SFVBTVKNSA-N
SMILES CCC=CCC(O)C=CC=CC=CC(O)CC=CCC=CCCC(=O)O

 Protectin D1Bioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Drug excretion in healthy human urine assessed as 3Z,6R,7E,9E,11Z,13S,15Z)-6,13-Dihyd...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4416598
Name: Anti-inflammatory activity in FVB mouse with zymosan-induced sterile peritonitis asse...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3383285
Name: Inhibition of LTB4-induced chemotaxis in human polymorphonuclear leukocytes incubated...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4416599
Name: Anti-inflammatory activity in FVB mouse with zymosan-induced sterile peritonitis asse...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3383287
Name: Anti-inflammatory activity in FVB mouse with zymosan-induced sterile peritonitis asse...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3383286
Name: Inhibition of LTB4-induced chemotaxis of human primary PMN at 0.01 to 100 nM pre-incu...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3383289
Name: Anti-inflammatory activity in FVB mouse with zymosan-induced sterile peritonitis asse...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3383288
Name: Antiinflammatory activity in mouse assessed as reduction of zymosan-induced neutrophi...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3241216
Name: Inhibition of LTB4-induced cell adhesion to fibronectin in human primary PMN at 0.1 t...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3383291
Name: Antiinflammatory activity in mouse assessed as reduction of zymosan-induced number of...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3242311
Total 38, Current Page 1 of 4
1
2
3
4

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxy-4,7,11,13,15,19-docosahexaenoic acid
10R,17S-dihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid
10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid
NPD1
PD1
neuroprotectin D1

 Protectin D1 | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of protectin D1?
A: Main uses of protectin D1: Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models[1][2].
Q: What is the molecular weight of protectin D1?
A: Molecular weight of protectin D1 is 360.48700.
Q: What is the Chinese name of 660430-03-5?
A: Chinese name of 660430-03-5 is 660430-03-5.
Q: What is the polar surface area (PSA) of protectin D1?
A: Polar surface area (PSA) of protectin D1 is 77.76000.
Q: What is the LogP of protectin D1?
A: LogP of protectin D1 is 4.49050.
Q: What is the CAS number of protectin D1?
A: CAS number of protectin D1 is 660430-03-5.
Q: What is the molecular formula of protectin D1?
A: Molecular formula of protectin D1 is C22H32O4.
Q: What is the English name of protectin D1?
A: The English name of protectin D1 is protectin D1.
Q: What is the SMILES notation of protectin D1?
A: SMILES notation of protectin D1 is CCC=CCC(O)C=CC=CC=CC(O)CC=CCC=CCCC(=O)O.
Q: What English synonyms does protectin D1 have?
A: English synonyms of protectin D1: (4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxy-4,7,11,13,15,19-docosahexaenoic acid, 10R,17S-dihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid, 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid, NPD1, PD1, neuroprotectin D1.

 Protectin D1factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.