OYYF-175

Modify Date: 2025-08-25 16:21:18

OYYF-175 Structure
OYYF-175 structure
Common Name OYYF-175
CAS Number 65829-22-3 Molecular Weight 307.32
Density N/A Boiling Point N/A
Molecular Formula C17H14FN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of OYYF-175


OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-

 Names

Name OYYF-175

 OYYF-175 Biological Activity

Description OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-
Related Catalog
Target

IC50: 2.36 nM (Escherichia coli DHFR)

References

[1]. Yue Li, et al. The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur J Med Chem. 2022 Jan 15;228:113979.

 Chemical & Physical Properties

Molecular Formula C17H14FN5
Molecular Weight 307.32
InChIKey HAPAUTSWUJUYGK-UHFFFAOYSA-N
SMILES Nc1nc(N)c2c(ccc3c2ccn3Cc2ccccc2F)n1
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