65829-22-3

65829-22-3 structure
65829-22-3 structure
  • Name: OYYF-175
  • Chemical Name: OYYF-175
  • CAS Number: 65829-22-3
  • Molecular Formula: C17H14FN5
  • Molecular Weight: 307.32
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-05-28 18:13:42
  • Modify Date: 2024-01-13 17:09:33
  • OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-

Name OYYF-175
Description OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-
Related Catalog
Target

IC50: 2.36 nM (Escherichia coli DHFR)

References

[1]. Yue Li, et al. The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur J Med Chem. 2022 Jan 15;228:113979.

Molecular Formula C17H14FN5
Molecular Weight 307.32
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