FA-Phe-Gly-Gly-OH

Modify Date: 2024-01-02 17:00:38

FA-Phe-Gly-Gly-OH Structure
FA-Phe-Gly-Gly-OH structure
Common Name FA-Phe-Gly-Gly-OH
CAS Number 64967-39-1 Molecular Weight 399.397
Density 1.3±0.1 g/cm3 Boiling Point 842.3±65.0 °C at 760 mmHg
Molecular Formula C20H21N3O6 Melting Point 245ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 463.2±34.3 °C

 Use of FA-Phe-Gly-Gly-OH


N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination[1].

 Names

Name N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
Synonym More Synonyms

 FA-Phe-Gly-Gly-OH Biological Activity

Description N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination[1].
Related Catalog
References

[1]. Hsu FL, et al. Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. Tainong No. 1), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities. J Agric Food Chem. 2002 Oct 9;50(21):6109-13.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 842.3±65.0 °C at 760 mmHg
Melting Point 245ºC (dec.)(lit.)
Molecular Formula C20H21N3O6
Molecular Weight 399.397
Flash Point 463.2±34.3 °C
Exact Mass 399.143036
PSA 137.74000
LogP 1.77
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.603
Storage condition −20°C
Water Solubility NH4OH 1 M: 50 mg/mL, clear to slightly turbid, yellow

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS OH2915000
HS Code 29321900

 Synthetic Route

~73%

FA-Phe-Gly-Gly-OH Structure

FA-Phe-Gly-Gly-OH

CAS#:64967-39-1

Literature: Pozdnev, V. F. J. Gen. Chem. USSR (Engl. Transl.), 1986 , vol. 56, # 3 p. 690 - 695,613 - 617

~%

FA-Phe-Gly-Gly-OH Structure

FA-Phe-Gly-Gly-OH

CAS#:64967-39-1

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617

~%

FA-Phe-Gly-Gly-OH Structure

FA-Phe-Gly-Gly-OH

CAS#:64967-39-1

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617

~%

FA-Phe-Gly-Gly-OH Structure

FA-Phe-Gly-Gly-OH

CAS#:64967-39-1

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617

~%

FA-Phe-Gly-Gly-OH Structure

FA-Phe-Gly-Gly-OH

CAS#:64967-39-1

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617

 Articles33

More Articles
Effect of power ultrasound pretreatment on peptidic profiles and angiotensin converting enzyme inhibition of milk protein concentrate hydrolysates.

J. Sci. Food Agric. 94(12) , 2420-8, (2014)

The use of power ultrasound as a pretreatment to enhance the hydrolysis of milk protein concentrate (MPC) and subsequent angiotensin converting enzyme (ACE) inhibitory activity has been studied. Liqui...

Assessment and optimization of kinetic methods for angiotensin-converting enzyme in plasma.

Clin. Chem. 39(2) , 312-6, (1993)

In the kinetic angiotensin-converting enzyme (ACE) method, a practical and optimal buffer is 80 mmol/L borate buffer at pH 8.2 (37 degrees C). A lag phase is detected in the reaction, and a 5-min incu...

Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme.

FEBS Lett. 550(1-3) , 84-8, (2003)

The somatic isoform of angiotensin-converting enzyme (ACE) consists of two homologous domains (N- and C-domains), each bearing a catalytic site. We have used the two-domain ACE form and its individual...

 Synonyms

Glycine, N-[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-phenylalanylglycyl-
N-[(2E)-3-(2-Furyl)prop-2-enoyl]-L-phenylalanylglycylglycine
N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine
N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanylglycylglycine
FAPGG
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