Schisantherin D

Modify Date: 2025-08-25 16:39:36

Schisantherin D Structure
Schisantherin D structure
Common Name Schisantherin D
CAS Number 64917-82-4 Molecular Weight 520.52700
Density N/A Boiling Point N/A
Molecular Formula C29H28O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Schisantherin D


Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects[1][2].

 Names

Name schisantherin D
Synonym More Synonyms

 Schisantherin D Biological Activity

Description Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects[1][2].
Related Catalog
Target

EC50: 0.5 μg/mL (HIV)[1]

References

[1]. D F Chen, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8.

[2]. Jin-Biao Xu, et al. Lignans from Schisandra chinensis ameliorate alcohol and CCl 4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR. J Ethnopharmacol. 2020 Aug 10;258:112813.

 Chemical & Physical Properties

Molecular Formula C29H28O9
Molecular Weight 520.52700
Exact Mass 520.17300
PSA 101.91000
LogP 4.66950

 Safety Information

Hazard Codes Xi

 Synonyms

schizantherin D
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